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In 2006, Shaklee Corporation marked its 50th year with a continued commitment to producing top quality products, to environmental citizenship, and to ongoing philanthropic endeavors. Founded on the philosophy of offering products in harmony with nature and good health, Shaklee adheres to the principles that were established by Shaklee’s founder, Dr. Forrest C. Shaklee. Ingredients must be as natural as possible and ingredients must reflect the most recent scientific and technological advances. The major priority for Shaklee is to use natural ingredients in the products whenever possible.

Shaklee defines "quality" as meeting or exceeding the highest standards in the industry, from product conception to market entry. A team led by Jamie McManus, MD, Chairman of Medical Affairs, Health Science and Education, is comprised of nutritionists, chemists and food scientists, who are involved in all stages of new product development and the continuing evaluation of existing products.

Shaklee is a leader in research, has powered numerous athletes including Olympic medalists, has provided NASA with a re-hydration drink for the astronauts for their re-entry to Earth's atmosphere for years, and was green before it was popular to be called green. The company philosophy includes Always Safe, Always Green and Always Works.